Best CBD Oil For Dogs With Seizures 2025: Review & Guide
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Watching your dog experience seizures—whether occasional or frequent—can be terrifying and emotionally draining. You’ve likely tried prescription medications, dietary changes, and even holistic therapies—yet the episodes keep happening. Here’s a hopeful alternative: CBD oil is gaining attention as a natural option to help manage canine seizures. But with so many brands on the market, how do you know which ones are actually effective and safe? Some products claim fast results, while others emphasize long-term support. So, what’s real, and what’s just hype? This guide will explore the best CBD oils for dogs with seizures, supported by real results, expert input, and the most important factors to consider before choosing a product. Let’s get into it—and help your pup find some much-needed relief and stability.
What Is CBD Oil?
CBD oil, or cannabidiol oil, is a natural extract derived from the hemp plant (Cannabis sativa). It is one of many compounds found in cannabis but is non-psychoactive, meaning it won’t get your dog “high” like THC (tetrahydrocannabinol), the primary psychoactive component in marijuana. The key difference between CBD and THC is how they interact with the body. While THC affects the brain’s receptors to create a “high,” CBD works differently, promoting relaxation and wellness without any intoxicating effects. That’s why CBD oil is considered safe for pets when used correctly.
Common Symptoms of Seizures in Dogs
How Does CBD Work on Dogs with Seizures?
CBD interacts with your dog’s endocannabinoid system (ECS)—a system of receptors that helps regulate neurological function, inflammation, and overall balance in the body. In dogs with seizures, abnormal electrical activity in the brain can lead to convulsions and neurological distress. CBD may help regulate this activity by supporting the ECS, promoting calmness, reducing seizure frequency, and improving overall brain function—helping your dog live a more stable, comfortable life.
The Science Behind CBD Oil & Dog Seizures
While still developing, current research offers insights into its effectiveness, though findings are mixed.
Scientific Studies
- Fifty-one epileptic dogs treated with CBD: Administered at 9 mg/kg/day, CBD led to a significant reduction in seizure frequency in dogs compared to placebo. Specifically, there was a 24.1% decrease in seizure days for dogs receiving CBD, while the placebo group experienced a 5.8% increase.
- Twenty-six epileptic dogs tried CBD: In this study, dogs receiving CBD oil at 2.5 mg/kg twice daily for 12 weeks showed a significant reduction in seizure frequency compared to the placebo group. The median change in monthly seizure frequency was a 33% reduction for the CBD group.
- Effects of CBD in fourteen dogs with refractory epilepsy: In this study, CBD was administered at 2 mg/kg every 12 hours for 3 months; the treatment resulted in a significant reduction in seizure frequency and seizure days compared to the placebo. Specifically, 6 out of 14 dogs exhibited a ≥50% reduction in seizure events during the CBD/CBDA treatment phase.
- Cannabidiol in canine epilepsy: This review article discusses the current understanding of CBD’s role in managing canine epilepsy. It highlights that tolerability studies in both healthy dogs and those with epilepsy have demonstrated that CBD is generally safe and well-tolerated, with only mild to moderate adverse effects reported.
Anecdotal Evidence
Many dog owners have reported improvements in their pets’ seizure frequency and severity after administering CBD oil. For instance, some have observed reduced seizure activity and improved overall quality of life in their dogs. While these accounts are encouraging, they are subjective and may be influenced by individual perceptions. Preliminary studies suggest the potential benefits of CBD oil for canine epilepsy; however, the evidence is still emerging, and more rigorous research is needed to confirm its efficacy and safety.
The Benefits
Here’s how CBD may help dogs with seizures:
- May reduce seizure frequency
- Helps calm overactive neurons
- Supports neurological health
- Improves overall quality of life
The veterinary community remains cautious regarding CBD use for canine seizures. While some veterinarians acknowledge potential benefits, they emphasize the need for more comprehensive research to determine optimal dosages, long-term effects, and possible drug interactions. Pet owners must consult with a veterinarian before introducing CBD into their dog’s regimen. Read our scientific-based article on all things CBD for dogs to learn more about the benefits and research.
Best CBD Oil For Dogs With Seizures
These are our top picks for the best CBD oil for dogs suffering from seizures.
Best Overall CBD Oil For Dogs With Seizures
HolistaPet
Who It’s For: For those who want the highest quality CBD oil for dogs with seizures at a great value.
CBD type: Full-spectrum
Price: $25.95 – $144.95
Oil source: USA, CO
THC: 0%
Potency (mg): 150, 300, 600, 1200 & 3000
Key Features
Save an extra 25% – 30% if you sign up for auto shipping. Just use this link to get started.
Best Health Specialized Line For Dogs With Seizures
Honest Paws
Who It’s For: Ideal for those who seek a CBD solution to target specific health issues such as seizures.
CBD type: Full-spectrum
Price: $39.95 – $99.95
Oil source: USA, CO
THC: Less than 0.3%
Potency (mg): 125, 250, 500 & 1000
Key Features
Get 15% off at Honest Paws with coupon code CANINEBIBLE. Use this link to get started.
My Video Review Experience
Best Isolate CBD Oil For Dogs With Seizures
Medterra CBD Pets
Who It’s For: Great option if your anxious dog has had adverse reactions to THC or if you want to avoid the risks of it completely.
CBD type: Isolate
Price: $19.99 – $39.99
Oil source: USA, KY
THC: 0%
Potency: 150mg, 300mg & 750mg
Key Features
My Video Review Experience
Get 25% off at Medterra with the coupon code CANINEBIBLE. Just use this link to get started.
More Options
Finding the right CBD oil for your dog’s seizures is essential to ensuring the best results. With various brands offering different formulations, potencies, and ingredients, choosing one that suits your dog’s specific needs is important. Whether you’re looking for organic hemp extracts, fast-acting formulas, or veterinarian-recommended options, we’ve compiled a list of the top CBD oils for dogs to help you make the best choice. Read our guide to the best CBD oils for dogs for other alternatives.
How Long Does CBD Take to Help With Seizures in Dogs?
CBD oil may begin to reduce seizure activity and promote neurological calm within 30 to 60 minutes of administration during acute episodes. However, for dogs with chronic or recurring seizures, consistent daily use is typically required for 1 to 2 weeks before noticeable improvements are observed in seizure frequency, duration, or severity. Factors like dosage, your dog’s size, and the underlying cause and intensity of their seizures all play a role in how quickly CBD takes effect.
💡 Want to learn more? Read our in-depth guide:
👉 How Long Does CBD Stay in a Dog’s System?
👉 How Long Does It Take for CBD to Work on Dogs?
CBD Dosage for Dogs with Seizures
The right CBD dosage depends on your dog’s weight, seizure level, and how they respond to CBD. A general rule of thumb:
- Mild Seizures: 0.25 mg per pound
- Moderate Seizures: 0.5 mg per pound
- Severe Seizures: 1 mg per pound
For best results, start with a low dose and gradually increase while monitoring your dog’s response.
📌 Need a detailed dosage chart? Check out our full guide:
👉 The Ultimate CBD Dosage Guide for Dogs (Infographic)
Other CBD Products to Treat Seizures In Dogs
The Bottom
CBD oil has emerged as a promising natural tool for helping manage seizures in dogs, offering support for neurological balance without the harsh side effects of some traditional antiepileptic medications. While more research is still needed, early studies and anecdotal reports suggest that high-quality, full-spectrum CBD oil may reduce the frequency and severity of seizures in some dogs. When choosing the best CBD oil for dogs with seizures, consider factors like potency, purity, third-party testing, and seizure-specific formulations. Every dog responds differently to CBD, so starting with a vet-approved dosage and monitoring their response over time is essential. With the right CBD product, a consistent routine, and veterinary support, you can help your dog enjoy a more stable, joyful life with fewer seizures and more peace.
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Sources
Canine Bible uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process and product review methodology to learn more about how we fact-check, test products, and keep our content accurate, reliable, and trustworthy.
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