10 Best Dog Allergy Medicine & Treatments: According to Vets
Canine Bible is reader-supported. We receive affiliate commissions via some of our links. Learn more.
This is the most comprehensive guide to finding the best dog allergy medicine. Allergies are a significant problem for dogs and can trigger a range of health issues, including digestive problems, skin issues, itching, hives, and more. So, what is the most effective allergy medicine for dogs? Picking the best allergy medicine for dogs depends on your dog’s symptoms, allergy severity, health conditions, and causes. Hence, it’s critical to research before choosing a dog allergy treatment option. In this article, we’ll go over the best dog allergy treatments, including prescription allergy medicine for dogs, over-the-counter dog allergy medicine, all-natural treatments, and treatment for specific allergy issues, and more. We also explain the risks associated with certain medicines, so you can address your concerns with your veterinarian. Let’s dive right in!
Best Allergy Medicine For Dogs — At Glance
Why you should trust us: Our writers, editors and in-house veterinarians spend hours analyzing and reviewing products and services to help find what’s best for you. Read the product review methodology and editorial mission to find out how we test, analyze, and rate.
The Research
Jump to: Full Reviews | Additional Info
The Best Dog Allergy Medicine According to Vets
The best allergy treatment for your dog depends on the severity of their symptoms, the type of allergy, and the frequency of allergic reactions.
Generally, antihistamines are a common way to provide allergy relief for dogs. Just like you might take Benadryl or Claritin for your allergies, these medications can also help your furry friend. However, it’s important to note that antihistamines are only effective in about 30% of dogs, according to research.[1] Another study indicated that 54% of dogs responded favorably to antihistamine treatments. Despite these statistics, strong anecdotal evidence suggests that antihistamines can be effective options for relieving dog allergies.
Antihistamines may initially work well, but they can lose effectiveness over time. Veterinary dermatologist Dr. Nicole Eckholm told Rover, “If an antihistamine is effective, you could continue using it as long as it remains effective. Sometimes, you can manage allergies with just that. Other times, as allergies progress, antihistamines are no longer effective.”[2]
Veterinary dermatologist Dr. Paul Bloom, DVM, DACVD, DABVP, notes that various antihistamines are available, with none being more effective than another. He recommends trying another antihistamine every 14 days if no improvement is observed until each has been tested for 14 days or an effective one is found.[3]
Corticosteroid therapies (topical or oral) are often the first choice for treating acute (more severe) and chronic inflammatory skin diseases, especially allergic dermatitis.[4] While steroids (corticosteroids) are more powerful and effective at treating allergy symptoms than antihistamines, their long-term use is not recommended due to possible severe and permanent side effects. They are best suited for short-term treatment. Alternatively, nonsteroidal immunosuppressants can be an excellent alternative to steroids for dogs requiring both short-term and long-term treatment, as they do not carry the side effects associated with steroids.
The most effective allergy treatment is immunotherapy (allergy shots), considered the gold standard for managing allergies and halting their progression. The success rate of immunotherapy ranges from 60% to 80%, making it the most effective long-term approach for controlling allergies.
Natural dog allergy treatments can also effectively manage dog allergies, but they are generally more suitable for mild cases and for preventing them. You must consult your vet to determine the best approach for your pet.
Prevention Is The Best Dog Allergy Medicine
The most effective strategy for managing allergies in dogs is prevention. Dog allergy kits can assist in identifying various types of allergies or intolerances, including those related to food, environmental factors, airborne substances, household items, supplements, medications, and more. Another practical method to identify what allergens are affecting your pet is through at-home dog allergy testing kits. Similarly, an at-home dog gut health test can offer valuable insights by analyzing your dog’s microbiome, helping you identify potential food sensitivities or allergens and tailor your diet accordingly.
While these tests should not be used solely to diagnose dog allergies, the results can be invaluable for understanding the condition. You and your veterinarian can use these results to create a tailored allergy treatment plan for your dog to avoid ingestion or exposure to potential allergens.
How to Pick The Best Allergy Medicine For Dogs
The Reviews
Jump to: The Research | Additional Info
Best Allergy Medicine For Dogs
There are several treatments available for canine allergies. Some require a veterinarian’s prescription, while others are available over the counter. Whether looking for the best daily allergy medicine for dogs to treat seasonal allergies, a stronger dog allergy med to treat chronic allergy cases, or stopping most dog allergy symptoms, these options can keep sniffles and itchy skin at bay.
Prescription allergy medicine for dogs falls into two categories:
Nonsteroidal Immunosuppressants
Nonsteroidal immunosuppressants are a class of medications that help manage allergies in dogs by suppressing the immune system’s response to allergens. These drugs are beneficial when other allergy treatments, like antihistamines or steroids, have not provided adequate relief. They work by inhibiting specific immune responses that lead to allergy symptoms. They do not have the broad systemic effects of traditional steroids (corticosteroids), making them a safer long-term option for allergy management. Nonsteroidal immunosuppressants are generally safer than traditional steroids, but they can still have side effects such as gastrointestinal upset (vomiting, diarrhea).
Overview
The Most Common Immunosuppressants
Corticosteroids
Corticosteroids, commonly known as steroids, are a class of medications used to manage allergies in dogs. Corticosteroids work by mimicking the effects of cortisol, a hormone produced by the adrenal glands. Cortisol is a potent anti-inflammatory hormone that helps your dog’s body mitigate the effects of inflammation and other stress-related responses caused by histamine and other pro-inflammatory substances. While these medications stop allergy symptoms, long-term side effects from steroids come with a whole host of adverse side effects, including urinary tract infections (UTIs), susceptibility to infections, and obesity, to name a few.
Overview
The Most Common Corticosteroids
Nonsteroidal immunosuppressants are a class of medications that help manage allergies in dogs by suppressing the immune system’s response to allergens. These drugs are beneficial when other allergy treatments, like antihistamines or steroids, have not provided adequate relief. They work by inhibiting specific immune responses that lead to allergy symptoms. They do not have the broad systemic effects of traditional steroids (corticosteroids), making them a safer long-term option for allergy management. Antihistamines work by blocking histamines, which are chemicals that the body produces in response to an allergen. When an allergic reaction occurs, the body releases histamines, which can lead to itching, swelling, and other symptoms associated with allergic reactions. By blocking the effect of histamines, antihistamines help reduce or prevent these symptoms.
Overview
Most Common Antihistamines
Over-the-counter (OTC) dog allergy medicines are readily available products designed to address various allergic reactions in dogs. Environmental factors, food, insect bites or stings, and other triggers can cause these reactions. OTC allergy medicines for dogs are typically antihistamines, but there are other OTC allergy meds for dogs you can buy for your dog. Please note that while OTC allergy medicines can provide temporary relief, they might not address the underlying cause of the allergy. Chronic or severe allergic reactions should be discussed with a veterinarian, who can recommend the best option.
Topical treatments for allergies are products that are applied directly to the skin to alleviate allergic reactions and associated symptoms. These treatments can come in various forms, such as creams, ointments, lotions, gels, and sprays. They are particularly beneficial when there’s itching with no clear origin. Furthermore, these treatments can serve as a supplementary solution alongside systemic treatments, like oral antihistamines.
Overview
The Most Common Topical Treatments
Allergen-specific immunotherapy, commonly called allergy shots, is designed to desensitize a dog’s immune system to specific allergens. By exposing the dog to controlled amounts of the allergen over time, the immune system is trained to tolerate it without eliciting an allergic response. The process begins with identifying the specific allergens causing reactions in the dog through allergy testing. Once identified, a specialized serum containing tiny amounts of these allergens is prepared. This serum is then injected into the dog regularly, with the allergen concentration gradually increasing over time. The consistent exposure in controlled doses aims to reduce and eventually eliminate the dog’s allergic response to those substances. Additionally, this therapy is a preferred alternative when the long-term use of medications, like steroids, is not desirable because of their potential side effects.
Overview
The Most Common Allergy Shots
Food allergies or intolerances are present in dogs that experience an allergic reaction or sensitivities to certain foods. The food elimination trial consists of selecting a special hypoallergenic diet for your dog with the help of your veterinarian. After gradually introducing this new diet over three to five days, you’ll strictly feed your dog this diet for the next eight to ten weeks. During this period, your dog must consume only this special food—no other treats, human food, flavored medications, chews, or anything else. Only hypoallergenic food should be given.
After the tenth week, if your dog stops itching on this new diet, it’s a strong sign they may have a food allergy. At this point, you can either continue with the hypoallergenic food or cautiously reintroduce other foods to see if the itching resumes. If you choose to reintroduce the food, you should do a gradual ingredient reintroduction, one by one. If symptoms reappear upon reintroduction, it’s indicative that the dog is allergic or intolerant to that ingredient. Reintroduction of ingredients is key because it allows you to pinpoint the culprit ingredient to avoid in the future, making it a recommended approach. It’s vital to adhere strictly to your veterinarian’s recommendations.
Overview
The Most Common Food Elimination Trials
Environmental dog allergy changes refer to modifications in a dog’s surroundings or lifestyle to reduce exposure to allergens. These environmental allergens can trigger allergic reactions in sensitive dogs, resulting in symptoms such as itching, sneezing, or digestive issues. By identifying specific allergens causing the reactions and then eliminating or minimizing the dog’s exposure to them, you can reduce or prevent allergic symptoms. This may involve changes such as using specific cleaning products, adjusting outdoor activity times, or installing home air filters.
Overview
The Most Common Environmental Dog Allergy Changes For Allergies
Natural dog allergy medicines refer to non-pharmaceutical remedies derived from natural sources intended to alleviate allergy symptoms in dogs. These treatments typically use herbs, natural supplements, and other organic substances believed to possess anti-inflammatory, antihistaminic, or immune-boosting properties. These remedies function by either bolstering the dog’s immune system, counteracting the inflammatory response of allergens, or directly combating the allergens themselves.
Overview
The Most Common Natural Dog Allergy Medicine
Homemade dog allergy medicines are remedies crafted at home using commonly available natural ingredients. These DIY treatments are often favored by pet owners who are wary of synthetic pharmaceuticals and prefer a more organic approach to their dog’s health. These treatments usually rely on the inherent properties of natural ingredients to soothe, heal, or prevent allergic reactions. They aim to bolster the dog’s immune response, alleviate symptoms, or create barriers against allergens.
Overview
The Most Common Homemade Dog Allergy Medicine (DIY)
EpiPen is an auto-injector brand that delivers epinephrine (adrenaline) quickly into the body. It’s primarily used to treat severe allergic reactions, also known as anaphylaxis. When someone, including a dog, experiences a severe allergic reaction, every second counts, and an EpiPen can be life-saving. Epinephrine works by narrowing blood vessels and opening airways in the lungs. This counteracts the severe drop in blood pressure and difficulty breathing that can occur during anaphylaxis. The auto-injector mechanism ensures that the medication is delivered rapidly and effectively.
Pet owners must consult a veterinarian before keeping an EpiPen for their dogs. They should be trained on the proper use of the device, storage, and the importance of seeking immediate veterinary care even after administration. Epipen offers a temporary solution, and a treated individual (or dog) still needs close medical attention following its use.
Overview
The Most Common Uses of EpiPen
The benefits of liquid dog allergy medicine are that they requires less digestion. They are already broken down, so your body receives the nutrients/medication faster. Here are some of your options.
Other Dog Allergy Treatment Mentions
Additional Information
Jump to: The Research | Full Reviews
Allergy Medicine For Dogs Dosage
The appropriate allergy medicine dosage for your dog depends on various factors, including the specific condition being treated, the dog’s size and medical history, and the type of medication (such as antihistamines or steroids). The severity of symptoms also plays a crucial role. Each dog requires a tailored dosage; for instance, the amount given to a pug would differ significantly from that given to a Great Dane. It is essential not to administer any medication to your dog without consulting your veterinarian.
What Is The Safest Allergy Medicine For Dogs?
When considering safety and side effects, natural supplements or ingredients are typically the safest allergy medicine for dogs. Antihistamines are the next safest option; they are generally well-tolerated by dogs and rarely cause side effects. Prescription medications are also available, with two primary choices: nonsteroidal immunosuppressants and corticosteroids. Nonsteroidal immunosuppressants are safer, though they may still have more severe side effects compared to natural over-the-counter (OTC) options and antihistamines. Corticosteroids, while effective, have the most severe side effects and are generally recommended only for short-term use.
Best Allergy Medicine For Dogs Reddit
There were numerous Reddit threads on dog allergy medications. Here are the cliff notes and the most recommended alternative on the platform.
It seems that a lot of people on Reddit turn to OTC antihistamines, with Benadryl and Zyrtec being one of the most popular options. Apoquel was also mentioned as a great alternative. Some dog parents also recommended a diet switch, and others complained about the high cost of vet-related allergy visits. They also discussed prevention as the most effective solution. Below are some popular threads.
Comment
byu/LadyKeystroke from discussion
indogs
Comment
byu/settersrclowns from discussion
indogs
Frequently Asked Questions
The Bottom Line & Alternatives
The array of treatments available means your dog doesn’t have to endure the discomfort of itchiness and other distressing allergy symptoms. We trust that this article has provided valuable insights, helping you navigate your dog’s allergy treatment options. The detailed information and comparisons clarify what each product offers, its mode of action, and other crucial aspects. It’s important to remember that dogs can have varied responses to medications. What works for one might not be suitable for another. Finding the proper treatment may require patience and collaboration with your veterinarian. As a proactive measure, focus on prevention as your primary strategy against allergens. Consider pet insurance and explore natural remedies, like CBD oil for dogs, to maintain your furry friend’s health and potentially reduce unforeseen veterinary expenses in the future.
Like It? Subscribe & Share!
Sources
Canine Bible uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process and product review methodology to learn more about how we fact-check, test products, and keep our content accurate, reliable, and trustworthy.
- Cook, C. P., Scott, D. W., Miller, W. H. Jr., Kirker, J. E., & Cobb, S. M. (2004). Treatment of canine atopic dermatitis with cetirizine, a second generation antihistamine: A single-blinded, placebo-controlled study. Can Vet J, 45(5).
- Bennett, J. (n.d.). How to Stop Dog Allergies With 5 Powerful Treatments That Work. The Dog People by Rover.com.
- Bloom, P. (2010, October 1). Just Ask the Expert: Are antihistamines effective in canine atopy? DVM 360.
- Vitale, C. (2006, June 1). The proper use of topical and oral corticosteroids. DVM 360.















