If your dog is constantly itching, licking, or struggling with skin irritation, allergies may be to blame. From food sensitivities to environmental triggers like pollen or dust, allergies can significantly affect your dog’s comfort and overall health. While a vet visit is always the first step, the right supplement can play a key role in managing symptoms and supporting your dog’s immune system. In this guide, we’ve reviewed the best dog allergy supplements that help target common issues like hot spots, dry skin, and seasonal allergies, making it easier for you to find the right solution for your pup’s needs.
Best Dog Allergy Supplements According to Science
While there is no single “best” supplement, research highlights several promising options that may help reduce allergy symptoms in dogs, particularly those targeting skin health, immune balance, and gut health.
Supplement Type
Main Benefit
Evidence Quality
Notes
Probiotic/Nutraceutical Blend
Reduces itching, improves skin
High
Fast symptom relief
Zinc + EFA + Biotin
Lowers lesions, reduces itching
Moderate
Best with allergy meds
Acupuncture/Herbal/Nutrition
Stabilizes allergic conditions
Low–Moderate
Alternative approach
Vegetable Oils (Omega-6)
May worsen allergies
Moderate
Use with caution
Omega-3
Reduces allergy symptoms
Strong
Both fish and flax oil work
Table sources: [1],[2],[3],[4],[5]
Always consult your veterinarian before changing your dog’s diet. You can get personalized nutritional advice from an online registered vet nutritionist through Vetster anytime, anywhere. You can also chat with an online vet to discuss your dog’s allergy symptoms and nutritional needs. If you’re unsure what’s triggering the reaction, an at-home dog allergy test can help identify specific food or environmental allergens. Pairing this with a dog gut health test can offer additional insights into your dog’s microbiome and help determine which nutrients may best support their immune system. These tools empower you to make informed choices and find the most effective allergy supplement for your dog’s unique needs.
Best Allergy Supplements For Dogs
Here are the best allergy supplements for dogs this year.
Best Overall Dog Allergy Supplement
4.7
★★★★★
Pet Honesty
Who It’s For: Ideal for dogs dealing with most allergy symptoms, including seasonal allergies, skin irritation, paw licking, or excessive itching.
Why we recommended it:Pet Honesty Allergy Support earns top marks for its thoughtful, vet-reviewed formulation. It combines natural ingredients such as colostrum, salmon oil (rich in omega-3 fatty acids), and probiotics that support both immune function and gut health, two key areas often overlooked in allergy treatment. Owners often report noticeable improvements in scratching and skin condition within a few weeks, which speaks to the overall effectiveness of the product. It’s also backed by NASC (National Animal Supplement Council) certification, which adds confidence in the product’s safety and manufacturing standards.
What sets it apart from competitors: Offers a multi-functional approach by blending immune-modulating colostrum with gut-supporting probiotics and anti-inflammatory oils. The inclusion of apple cider vinegar (for its antifungal and antibacterial properties) is a unique touch that isn’t commonly found in similar products.
Best Supplement For Dogs With Itchy Skin From Allergies
4.9
★★★★★
Natural Dog Company
Who It’s For: Dogs suffering from itchy skin, frequent scratching, dull coats, or excessive shedding—especially those prone to seasonal allergies or dry, sensitive skin.
Why we recommended it:Natural Dog Company Omega Skin & Coat Chews, Vet Strength Supplement delivers a hefty dose of essential omega‑3 fatty acids—2.3× more EPA and 2.7× more DHA than standard formulas—which helps recalibrate the skin’s inflammatory response and boosts hydration from within. The blend also includes biotin and vitamin E, which support cell regeneration and overall coat health. Owners frequently report “noticeable improvement in skin health” within a few weeks and praise the chewable format for being easy to administer.
What sets it apart from competitors: The use of DHA Gold (sourced from marine microalgae) and wild Alaskan salmon oil ensures a rich, bioavailable source of omega-3s. The product is also eco-conscious, with recyclable packaging and upcycled ingredients, and is manufactured in GMP-certified, FDA-registered facilities.
Best Dog Allergy Supplement For Seasonal Allergies
4.6
★★★★★
Now Pets
Who It’s For: Designed for dogs that struggle with seasonal allergies—especially those prone to histamine-triggered reactions like sneezing, itchy skin, or ear irritation.
Why we recommended it:NOW Foods Pet Allergy Supplement is veterinarian-formulated, a chewable tablet that blends multiple botanicals—100 mg quercetin, nettle leaf, turmeric, bromelain, burdock, and licorice—to help maintain healthy histamine levels and reduce inflammation. The NASC certification and GMP standards mirror high-quality assurance, and the non-GMO label adds another layer of trust. Owners frequently report relief within a few weeks, noting calmer skin and less scratching. Dr. Barbara Royal, DVM, vet, confirms that it works well for dogs of various sizes—including those over 80 lbs.—and life stages.
What sets it apart from competitors: NOW Pets takes a holistic herbal approach, tackling allergy symptoms from multiple angles. The quercetin-and-nettle combo mimics natural antihistamine activity, while turmeric and bromelain offer anti-inflammatory support. The inclusion of burdock and licorice adds skin-nourishing benefits that aren’t always present in mainstream options.
Best Liquid Dog Allergy Supplement
4.6
★★★★★
Vital Pet Life
Who It’s For: Pet parents who want a natural, easy-to-administer option that supports skin and coat health, reduces itching, and promotes overall wellness, including joint and cognitive function.
Why we recommended it:Vital Pet Life Fish Oil (Salmon & Pollock) offers a potent dose of essential omega‑3 fatty acids—EPA and DHA—in their natural triglyceride form. Clinical information from the brand indicates that each 5 mL pump delivers a minimum of 400 mg EPA and 500 mg DHA, totaling 900 mg omega-3s. These fats are well-known for supporting skin barrier integrity, easing inflammation, and boosting coat health. The pump dispenser makes dosing effortless and precise. Plus, the choice of triglyceride form improves absorption compared to ethyl ester oils. The brand also offers clear labeling—no hidden ingredients, just clean nutrition.
What sets it apart from competitors: This formula combines both wild-caught Alaskan salmon and pollock, providing a rich source of omega-3s along with essential trace minerals like selenium, zinc, and phosphorus from whole fish sources. It’s Orivo-verified and free from artificial additives, maintaining purity and transparency.
Best Human-Grade Dog Allergy Supplement
4.7
★★★★★
JustFoodForDogs
Who It’s For: Dog owners who want a supplement made with recognizable, whole-food ingredients and no artificial preservatives, fillers, or synthetic ingredients
Why we recommended it:JustFoodForDogs Skin & Allergy Aid is vet‑developed, NASC‑certified, and cold‑pressed to preserve key nutrients, meaning more live probiotics and less nutrient loss from high‑heat processing. That careful approach supports both the immune response (via probiotics and prebiotics, such as MOS) and skin hydration (via algae oil rich in EPA and DHA). It’s made from real, human-grade superfoods—blueberries, broccoli, cranberries, dates, and carrots—and uses plant-based algae oil instead of fish oil, reducing possible contaminants and offering a more sustainable omega-3 source.
What sets it apart from competitors: The cold-pressed process preserves delicate vitamins and probiotics more effectively than extrusion. Plus, its clean‑ingredient philosophy appeals to pet parents who want total transparency from farm to bowl.
Best Allergy Supplement For Senior Dogs
4.9
★★★★★
Zesty Paws Senior Advanced
Who It’s For: Senior dogs dealing with seasonal allergies, itching, paw licking, watery eyes, or digestive upset related to immune system challenges.
Why we recommended it:Zesty Paws Senior Advanced Allergy & Immune Bites delivers a potent combination of immune and allergy support—340 mg quercetin (a natural antihistamine), 400 mg EpiCor® fermentate to bolster immune defenses, colostrum to support histamine balance, and omega‑3‑rich salmon oil for skin and coat health. It’s also packed with prebiotics (PreforPro®) and a 6‑strain probiotic blend (1 billion CFU) to support gut immunity—a crucial component for older dogs whose digestion may falter. This thoughtfully layered approach addresses allergy symptoms and promotes overall health, rather than focusing solely on one aspect.
What sets it apart from competitors: The inclusion of cutting-edge, patented ingredients like EpiCor and PreforPro demonstrates scientific rigor, and they’ve avoided artificial preservatives and colors. The chews are soft and palatable, making them easy for seniors with dental issues to enjoy.
Best Powder Dog Allergy Supplement
4.5
★★★★★
BIXBI
Who It’s For: Dog parents seeking USDA‑certified organic support that’s gentle, minimal in ingredients, and safe even for pets with food sensitivities.
Why we recommended it:BIXBI Skin & Coat Support uses a proprietary blend of organic mushrooms—including cordyceps, coriolus versicolor, king trumpet, maitake, reishi, and beech—which are rich in polysaccharides and antioxidants. These mushrooms have been shown to help balance overactive immune responses, reduce inflammation, and protect dermal cells from oxidative damage. The supplement is formulated with input from veterinarians and immunologists, and is certified organic by Oregon Tilth and the National Animal Supplement Council, ensuring both purity and quality.
What sets it apart from competitors: Rather than relying on additives or single-herb blends, this stands out thanks to its all‑organic, multi-mushroom blend backed by immune science. It’s one of the few allergy supplements with USDA organic certification and full transparency—no fillers or artificial ingredients. Its eco-conscious recyclable packaging also aligns with sustainability-minded buyers.
Best Allergy Supplement for Dogs With Sensitive Stomachs
4.7
★★★★★
Chew + Heal Labs
Who It’s For: Dogs that need allergy relief but struggle with tummy sensitivities.
Why we recommended it:Chew + Heal Labs Omega Skin & Coat delivers a well-rounded mix of omega‑3, ‑6, and ‑9 fatty acids—sourced from salmon, fish, and flaxseed oils—combined with skin-supporting vitamin E, zinc, biotin, and critical minerals like calcium and phosphorus. The inclusion of brewer’s yeast provides B vitamins, while prebiotics and probiotics support digestive health and immune function. At approximately 43.7 kcal per 3-chew serving (5,109 kcal/kg), it avoids an excessive caloric load.
What sets it apart from competitors: The blend’s multi-nutrient profile—featuring digestive enzymes and gut-balancing probiotics—is rare among skin-and-coat supplements, making it a gentler choice for pups with sensitive stomachs. It’s also produced in FDA-approved U.S. facilities, and vets appreciate that it supports skin and digestion in a straightforward chew.
Best Clinically-Proven Dog Allergy Supplement
4.7
★★★★★
Dechra
Who It’s For: Particularly ideal for dogs that have not responded well to antihistamines or topical treatments and need a supplement that supports their skin barrier system internally.
Why we recommended it:Redonyl Ultra delivers ultra‑micronized palmitoylethanolamide (PEA‑um), a lipid naturally produced in animals, known for stabilizing mast cells and reducing histamine and inflammatory mediators, helping dogs stop scratching at the source. In a double‑blind, 8-week study involving 160 client‑owned dogs, veterinary assessments rated 75% of dogs as having “sufficient,” “good,” or “excellent” skin improvement, with only four mild and fully reversible side effects reported. Its hypoallergenic chew base excludes wheat, beef, and chicken, making it safe for pups with common protein sensitivities.
What sets it apart from competitors: Redonyl’s defining advantage is its ultra-micronized PEA, which dramatically improves absorption compared to other forms. Data shows 99.9% of particles are under 6 µm—great for delivery deep into inflamed tissue. Unlike many allergy supplements that combine herbs or fatty acids, Redonyl targets the mast cell cascade, aiming to stabilize immune cells that trigger itching directly. It’s patent-protected, veterinarian-formulated, and designed to integrate seamlessly into existing dermatological protocols.
Best On-The-Go Dog Allergy Supplement
4.7
★★★★★
MAEV
Who It’s For: Active pups or traveling dogs needing a portable boost to support skin health and manage seasonal or itch-related allergies on the go.
Why we recommended it:Maev Skin & Coat Supplement Bars are PhD vet-formulated, USDA-certified, AAFCO-compliant, and pack a potent dose of omega-3s from fish oil, supporting hydration, reduced shedding, and fewer hotspots. The formula includes vitamin E and chia seeds, providing antioxidant support and nourishing the skin barrier. Additionally, with only eight clean, recognizable ingredients—such as coconut flakes, peanut butter, and gelatin—these bars provide balanced nutrition in a travel-friendly format. Also ideal for pet parents who want human-grade, raw nutrition tucked into a simple daily topper or snack, especially useful for dogs that get stressed on outings or during boarding.
What sets it apart from competitors: Unlike bulky containers or liquid oils prone to spillage, these individually wrapped bars are shelf-stable, easy to stash in backpacks or travel kits, and don’t require refrigeration. The flash-frozen raw format ensures nutrient integrity, giving active dogs a fresh-like supplement anywhere.
Best Puppy Allergy Supplement
4.8
★★★★★
Zesty Paws
Who It’s For: Puppies (up to about 1 year old) experiencing seasonal allergy signs—such as itchy skin, sniffles, or mild ear irritation—and those needing immune and gut-health support.
Why we recommended it:Zesty Paws Puppy Allergy & Immune Bites features a blend of colostrum (for immune support), EpiCor® Pets (a postbiotic for immune balance), astragalus root (an adaptogen), and a 6-strain probiotic blend to address allergies from multiple angles. This combination not only helps maintain normal histamine levels and soothe skin irritation but also supports digestive health, which is closely linked to immune response in puppies. The formula is developed with quality, research-backed ingredients and is designed to be both effective and easy to give.
What sets it apart from competitors: Multi-functional approach and puppy-specific formulation. The chews are made with premium ingredients and contain no artificial flavors or preservatives, which is especially important for young, sensitive digestive systems.
Best For Hot Spots, Skin Irritation & More
4.6
★★★★★
Ultra Oil Skin & Coat Supplement
Who It’s For: Ultra Oil is made for dogs with severe or prone to dry, itchy skin, breakouts, hot spots, dandruff, or excessive shedding.
Why we recommended it:Ultra Oil Skin & Coat Supplement for Dogs delivers a perfectly balanced blend of omega-3, -6, and -9 fatty acids from cold-pressed hempseed, flaxseed, fish (sardine and anchovy), and grapeseed oils. With fatty acid ratios like 25% omega‑3, 45.7% omega‑6, and 14.9% omega‑9, it reinforces the skin’s natural barrier, reduces inflammation, and promotes healing in irritated or chafed spots. Enhanced with vitamin E, A, C, zinc, and selenium, it supports tissue repair and healthy immune function. Most users report noticeable relief within days—especially reduced scratching and faster healing of hot spots—and full effect in 2–8 weeks.
What sets it apart from competitors: Ultra Oil’s USP is its perfectly formulated omega blend, using all-natural, human-grade, cold-pressed oils—all sourced sustainably (Peruvian fish, Canadian hemp). It stands out by including all three key omegas; many fish-oil supplements lack omega‑9. There’s no strong fish smell—thanks to neutral oils like hemp and grapeseed—and it boasts rigorous supplementation with fat-soluble vitamins and minerals.
The Bottom Line
Finding the right allergy supplement can make a world of difference in your dog’s quality of life, helping to reduce constant itching, soothe irritated skin, and support a stronger immune response. While no supplement is a cure-all, the best ones are backed by high-quality ingredients, positive reviews, and real results. Whether your dog struggles with seasonal allergies, food sensitivities, or skin flare-ups, the options we’ve highlighted offer targeted relief to help them feel more comfortable. Always consult with your veterinarian before introducing any new supplement, and monitor your dog’s response to find the best fit.
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Sources
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